![]() ![]() ![]() Nervous system disorders: Headache (oral) drowsiness (inhalation/endotracheal). Musculoskeletal and connective tissue disorders: Arthralgia, arthropathy (IV). Metabolism and nutrition disorders: Acidosis (IV). General disorders and administration site conditions: Pyrexia, chest tightness malaise, facial pain (IV). Gastrointestinal disorders: Nausea, vomiting, stomatitis diarrhoea, abdominal pain (oral). Stevens-Johnson syndrome, Lyell's syndrome), generalised urticaria (oral).īlood and lymphatic system disorders: Thrombocytopenia (IV).Ĭardiac disorders: Tachycardia cardiac arrest (IV).Įar and labyrinth disorders: Tinnitus (oral).Įye disorders: Eye irritation, pain or swelling, blurred vision. Rarely, bronchospasm serious skin reactions (e.g. Significant: Increased risk of upper gastrointestinal haemorrhage (oral), small increase in prothrombin time (IV). Recommendations may vary among countries and individual products (refer to specific product guidelines). Volume of the diluent must be adjusted to consider the age and weight of the patient. Refer to specific product guidelines for further dosing information.Ĭhild: 21-hour regimen: 5-20 kg: Initially, 150 mg/kg in 3 mL/kg of diluent via infusion over 1 hour, followed by 50 mg/kg in 7 mL/kg of diluent infused over 4 hours and then 100 mg/kg in 14 mL/kg of diluent infused over 16 hours 21-40 kg: Initially, 150 mg/kg in 100 mL of diluent infused over 1 hour, followed by 50 mg/kg in 250 mL of diluent infused over 4 hours and then 100 mg/kg in 500 mL of diluent infused over 16 hours ≥41 kg: Same as adult dose. ![]() Treatment may be continued using the same dose and rate as the 3rd infusion depending on the individual clinical evaluation. Adult: 21-hour regimen: Initially, 150 mg/kg in 200 mL of diluent via infusion over 1 hour, followed by 50 mg/kg in 500 mL of diluent infused over the next 4 hours and then 100 mg/kg in 1,000 mL of diluent infused over the next 16 hours. ![]()
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